Nagaspurthy Reddy Anugu, MD¹, Sanjay Kumar, MD², Philip Fernandes, MD³, Hernando Lyons, MD⁴

¹Department of Pediatrics, Henry Ford St. John Children’s Hospital, Detroit, MI, Email: nanugu1@hfhs.org.
²Department of Pediatrics, Division of Pediatric Gastroenterology, Henry Ford St. John Children’s Hospital, Detroit, MI, and Wayne State University School of Medicine, Detroit, MI.
³Department of Pediatrics, Henry Ford St. John Children’s Hospital, Detroit, MI.
⁴Department of Pediatrics, Division of Pediatric Gastroenterology, Henry Ford St. John Children’s Hospital, Detroit, MI, and Wayne State University School of Medicine, Detroit, MI.

Corresponding Author’s information: Nagaspurthy Reddy Anugu, Department of Pediatrics, Henry Ford St. John Children’s Hospital, Detroit, MI, USA.

Citation: Nagaspurthy Reddy Anugu, Sanjay Kumar, Philip Fernandes, Hernando Lyons, (2026). Unusual Culprit: Upper Gastrointestinal Bleed Following Influenza-A Infection in a Child. American J Case Rep Clin Imag. 2026; Feb, 4(1), 1-3.

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Abstract:

Background: Influenza virus infection is generally self-limited and uncomplicated in healthy children, but it is often associated with significant morbidity and mortality worldwide. Influenza is a respiratory illness; however, gastrointestinal (GI) symptoms are common and include nausea, vomiting, diarrhea, and abdominal pain. Significant GI complications such as gastrointestinal bleeding or perforation are rare, with only a few cases reported in the literature. Here, we present a rare case of recurrent hematemesis in a pediatric patient with acute influenza infection. Case Report: We report a case of a six-year-old male with respiratory symptoms and hematemesis with positive influenza A infection. Influenza should be considered in the differential diagnosis of pediatric patients presenting with respiratory illness and hematemesis during the influenza season.  Conclusion: This case highlights the rare but serious presentation of hemorrhagic gastritis presenting with hematemesis in the setting of acute Influenza infection.

MeSH Keywords: Hemorrhagic gastritis, Influenza A, Pediatrics, Upper Gastrointestinal Bleed.