Sumeet Bhardwaj, Yuan Xie, Ali H. Thahab, Affan Naveed, Omer Khan, Kevin Tu, Thinh Mai

Kansas City University College of Osteopathic Medicine, Kansas City, USA.

Corresponding Author: Sumeet Bhardwaj, Kansas City University College of Osteopathic Medicine, Kansas City, USA, Email: theranger122@gmail.com.

Citation: Sumeet Bhardwaj, Yuan Xie, Ali H. Thahab, Affan Naveed, Omer Khan, Kevin Tu, Thinh Mai (2025). An Uncommon Psychiatric-Dominant Presentation of Severe Hypothyroidism in a Young Adult. American J Case Rep Clin Imag. 2025; Nov, 3(1),XX-XX.

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Abstract

Severe hypothyroidism can manifest with neuropsychiatric symptoms, but cases dominated by psychiatric features, particularly in young adults, are rare and diagnostically challenging. We present the case of a 29-year-old male medical student with a history of autoimmune comorbidities who developed progressive anxiety, cognitive slowing, and depressive symptoms in the absence of overt somatic signs. Thyroid testing revealed profound hypothyroidism secondary to Hashimoto’s thyroiditis. Psychiatric symptoms improved significantly following initiation of levothyroxine, suggesting a causal connection. This case underscores the importance of screening for thyroid dysfunction in patients with new-onset psychiatric symptoms and highlights an atypical presentation of 'myxedema madness' in a young adult male.